WebJun 21, 2014 · The flexibility-rigidity index (FRI) is a newly proposed method for the construction of atomic rigidity functions required in the theory of continuum elasticity … WebMotivated by the success of flexibility-rigidity index (FRI) in biomolecular flexibility analysis and drug design, we propose an FRI-based model for quantitatively …
[1609.04306] Generalized flexibility-rigidity index
WebOct 26, 2015 · Flexibility-rigidity index (FRI) has been proposed as an accurate and efficient approach for protein flexibility analysis. In this work, we introduce FRI for the flexibility analysis of protein-nucleic acid complexes. We demonstrate that a multiscale strategy, which incorporates multiple kernels to capture various length scales in … WebNov 21, 2013 · The flexibility-rigidity index (FRI) is a newly proposed method for the construction of atomic rigidity functions required in the theory of continuum elasticity … ccbsa sharepoint
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WebFlexibility-rigidity index (FRI) has been developed as a robust, accurate and efficient method for macromolec-ular thermal fluctuation analysis and B-factor prediction. The performance of FRI depends on its formulations of rigidity index and flexibility index. In this work, we introduce alternative rigidity and flexibility formulations. WebOct 1, 1991 · The interrelationship of measures of rigidity-flexibility and of psychometric intelligence is examined. The latent factors of Attitudinal Flexibility, Motor-Cognitive Flexibility, and Psychomotor ... WebMar 15, 2024 · Flexibility and rigidity index (FRI) was proposed for protein flexibility analysis. It was shown to outperform essentially all other existing methods in normal mode analysis and B-factor prediction for over 400 proteins [9], [52], [51], [55]. The present work explores the potential power of the FRI method for geometric modeling and for ... ccbsa - wadeville