WebKeywords: prostate cancer; aggressiveness; folate metabolism; genetic variants; SNP; interaction 1. Introduction Prostate cancer (PCa) is the most common incident cancer and the second leading cause of cancer death (11%) among American men [1]. PCa is a complex and heterogeneous disease. WebDec 13, 2016 · Galectin-3 (Gal-3), an oncogenic pro-inflammatory protein, has been suggested as a possible complementary diagnostic candidate to prostate specific antigen (PSA) blood test for prostate cancer patients. ... Relative Gal-3 and relative PSA levels in patients at different clinical states of prostate cancer. Gal-3 and PSA concentrations …
Lucas Gentilini - Sales Specialist - Sartorius LinkedIn
WebOptimal therapy of biochemically relapsed prostate cancer (BRPC) after local treatment is elusive. An established modified citrus pectin (PectaSol®, P-MCP), a dietary polysaccharide, is an established antagonist of galectin-3, a carbohydrate-binding protein involved in cancer pathogenesis. WebApr 20, 2014 · Galectin-3 (Gal-3) is a β-galactoside binding and multifunctional lectin. It has been regarded as a target because of its important roles in many diseases, such as cancer (Smith et al., 2024; Song et al., 2014), fibrosis (Martínez-Martínez et al., 2015), and so on. Many researches presented Gal-3 blocking for disease inhibition. chapter 5 analytic trigonometry answers
Galectin-3 Regulates Mitochondrial Stability and Antiapoptotic …
WebGalectin-3 expression and function in prostate cancer. In other cancer types, Gal-3 expression increases throughout disease progression, Citation 37 whereas Gal-3 expression in prostate cancer is notably different. Gal-3 is strongly expressed in the early stages of prostate cancer, but this expression gradually decreases over disease ... WebAbstract. We investigated the role of galectin-3 in metastasis of human breast carcinoma BT549 cells using the experimental liver metastasis model. Underlying mechanisms were … WebElevated tissue expression of galectin-3 has been described in a number of neoplasms, including breast, stomach, prostate, and CNS cancers. 20–24 The role of galectin-3 as a protein influencing tumor size, proliferation of neoplastic cell lines and increasing metastatic potential, eg, in in breast cancer, has been emphasized. 25 The ... chapter 5 anatomy