WebNov 29, 2024 · Reference range for B12 is 180-914 ng/L. Patients were determined to be B12 deficient if B12 level was <180 ng/L, or if B12 was 150-400 ng/L with elevated MMA and macrocytosis in the absence of significant renal dysfunction, defined as serum creatinine ≥2.0 mg/dL. Results Records of 326 patients (150 female) were reviewed. WebSerum MMA levels may also be high in patients with thyroid disease or bacterial overgrowth in the small intestine. It may also be high in pregnant women or infants suffering from a rare genetic disease called methylmalonic acidemia. However, if your uMMA levels are high, you probably have B12 deficiency. Holotranscobalamin (HoloTC)
Methylmalonic acid (MMA) Pernicious Anaemia Society
WebFeb 12, 2024 · MMA - 352 Unbound B-12 (transcobalamin) - < 88 (it was 122 in August) B-12 - > 2000 (The most recent shot was 10 days previous) I believe, despite the elevated b12 result that this indicates a deficiency? My only potential symptom is muscle cramping in my feet on a nightly basis and memory problems... I do have Hashimoto’s as well. WebHigh MMA levels can be a sign of a vitamin B12 deficiency. Vitamin B12 deficiency can lead to serious health problems including anemia, a condition in which your blood has a lower … chittenden county vermont vital records
Methylmalonic Acid (MMA) Test: MedlinePlus Medical Test
WebFeb 1, 2009 · Serum elevations in homocysteine and methylmalonic acid result from defective biochemical processes in folate and B 12 deficiencies, and could be used to clarify the cause of megaloblastic anemia,... WebBackground The prevalence of vitamin B 12 deficiency, defined as an elevated concentration of plasma methylmalonic acid (P-MMA), has been estimated to be 15% to 44% in the … WebPatients with serum vitamin B12 201 to 350 picograms/mL together with an elevated MMA can be considered to have probable vitamin B12 deficiency. Diagnosis is confirmed if vitamin levels normalise and serum vitamin B12 rises with adequate vitamin B12 treatment. MMA Can be elevated (i.e., >0.4 micromol/L) with folate deficiency. grass fed mac and cheese