WebNational Center for Biotechnology Information WebFeb 13, 2024 · The results of our study revealed that male microchimerism in the endometrium is widely present in all groups of patients irrespective of endometriosis and pregnancy history. A large number of reports indeed substantiate the notion of the widespread presence of male microchimerism in human females [28,29,30,31,32].
Male microchimerism in the human female brain - PubMed
WebResults: Male microchimerism was found in 21% of women overall. Healthy women and women with RA did not significantly differ (24% vs 18%). Results ranged from the DNA … Microchimerism is the presence of a small number of cells in an individual that have originated from another individual and are therefore genetically distinct. This phenomenon may be related to certain types of autoimmune diseases although the responsible mechanisms are unclear. The term comes from … See more Human In humans (and perhaps in all placentals), the most common form is fetomaternal microchimerism (also known as fetal cell microchimerism or fetal chimerism) whereby cells from a See more Several studies have identified male DNA in both the human and mouse brains of mothers following pregnancy with a male fetus. It has been suggested that the fetal-derived cells can differentiate into those capable of presenting neurotypical immunomarkers on … See more Fetal T cells accumulate during in utero development. Even though the fetus is exposed to noninherited maternal antigens (NIMAs), fetal CD4 T cells are capable of alloantigen-induced proliferation, preferentially differentiating to Treg cells and preventing a … See more Microchimerism has been implicated in autoimmune diseases. Independent studies repeatedly suggested that microchimeric cells … See more There are many mechanisms at the maternal-fetal interface to prevent immune rejection of fetal cells. Nevertheless, systemic immunological changes occur in pregnant women. For example, condition of women suffering from autoimmune disorders (e.g. … See more NIMA-specific tolerance causes some interesting immunological phenotypes: sensitization to erythrocyte Rhesus factor (Rh) antigens is reduced among Rh- women born to Rh+ … See more The severity of preexisting autoimmune disorders is reduced during pregnancy and it is most apparent when fetal microchimeric cells … See more gluten free clip art free
Male microchimerism in women without sons: …
WebDec 11, 2024 · Indeed, significant male microchimerism (>20%) has been detected in women without any known male pregnancy ( 30 ), making possible an immune response to male-specific proteins that remains detectable long after initial exposure. Caution is warranted in interpreting our finding, however, given our small sample of women with no … WebOct 15, 2002 · The use of male DNA as a measure of FM can be confounded by other potential sources of microchimerism. Cells are known to engraft and persist between … WebResearch is currently investigating whether male-pattern neural development is a direct consequence of Y-chromosome-related gene expression or an indirect result of Y-chromosome-related androgenic hormone production. Microchimerism. The presence of male chromosomes in fetal cells in the blood circulation of women was discovered in 1974. gluten free clubhouse crackers