The disgenet database
WebJul 4, 2024 · Potential disease-related genes were collected from the DisGeNET database and the OTP. The DisGeNET database has been used to study a variety of biomedical issues, and it contains one of the largest publicly available collections of genes and variants related to human diseases for investigating the molecular basis of specific diseases . WebSep 9, 2024 · Performance evaluation using held-out data, Perturb-seq datasets, and the mouse cell atlas combined with the DisGeNET database demonstrates the improved accuracy and biological interpretability of SCING compared to existing methods. We applied SCING to the entire mouse single cell atlas, human Alzheimer’s disease (AD), and mouse …
The disgenet database
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WebMar 28, 2024 · We annotated the candidate genes in the DisGenet database. Much of the information we found is related to lupus, which indicates that the candidate genes in this study are important in the pathogenesis of lupus and have a certain degree of credibility. Among the four bioinformatic analyses, CDC27 was obtained using three methods. WebJan 1, 2024 · The DisGeNET Cytoscape App is an open source Cytoscape 3.x App designed to visualize, query and analyze a network representation of the gene-disease and the variant-disease associations contained in DisGeNET. The structure of the sqlite version of the DisGeNET database that supports the App is shown at the DisGeNET website 2.
WebJan 8, 2024 · DisGeNET covers the full spectrum of human diseases as well as normal and abnormal traits. The current release covers more than 24 000 diseases and traits, 17 000 … WebFucosidosis Type I: disease : Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
WebNational Center for Biotechnology Information WebDec 15, 2024 · DisGeNET database was applied to retrieve IS-related diseases and their corresponding genes. “Ischemic stroke” was used as index-disease (Index-disease-id: C0948008), and the “associated diseases” were obtained. According to the number of shared genes with IS, five CNS diseases were selected as examples for further …
WebDisGeNET is a comprehensive gene-disease association database that integrates associations from several sources that covers different biomedical aspects of diseases. In particular, it is focused on the current …
WebAug 18, 2024 · The DisGeNET database includes genetic data on the full spectrum of human diseases as well as normal and abnormal traits (Piñero et al., 2015, 2024, 2024). This database integrates data of human gene-disease associations from several repositories including single gene, complex multigenic, and environmental diseases, integrated by … how many carbs are in potstickersWebApr 4, 2024 · For this purpose we collected gene-disease associations with T2DM and their scores from the DisGeNET database regarding the 41 genes present in the 19 structures, genes with such scores are shown as black triangles in Fig 2, and we also report the DisGeNET score that indicate strength of the gene-disease association in S4 Table. The … how many carbs are in pomegranate seedsWebApr 15, 2015 · The DisGeNET Cytoscape plugin allows to visualize, query and analyse a network representation of DisGeNET database ( 12, 13). The GDAs are represented as bipartite graphs, in which genes and diseases are the vertices and the associations are represented as edges. The data can also be analysed from a gene-centric or a disease … how many carbs are in pretzelsWebOur findings suggest that the TES gene functions as a tumor suppressor gene and is frequently silenced by hypermethylation and loss of heterozygosity in ovarian cancers. Down regulation of TES was shown to be correlated with tumor differentiation (p = 0.035) and prognosis (p = 0.035, log-rank test). how many carbs are in pork ribsWebDownload scientific diagram Top 10 Scored Disease Associations for SQLE in DisGeNET Database. from publication: High Squalene Epoxidase in Tumors Predicts Worse Survival in Patients With ... how many carbs are in pico de galloWebMay 4, 2024 · Querying the DisGeNET database and RDF we found that 58.7% of the rare diseases are annotated with a disease superclass term from MeSH (medical subject headings). The top ten of superclass terms ... how many carbs are in pretzel sticksWebDisGeNET is a discovery platform containing one of the largest publicly available collections of genes and variants associated to human diseases ( Piñero et al., 2024; Piñero et al., … The DisGeNET database integrates information of human gene-disease … The DisGeNET-RDF Linked Dataset is an alternative way to access the DisGeNET … The DisGeNET database is made available under the Attribution-NonCommercial … The DisGeNET Cytoscape App is designed to visualize, query and analyse a network … DisGeNET-RDF Schema. The data model of the RDF representation of DisGeNET is … The functions in DisGeNET allow filtering the information using several metrics in … DisGeNET data can be obtained in different ways: by downloading the SQLite … Reload Data ... Toggle navigation CLINICAL BIOMARKERS COVID-19 DisGeNET data collection Version 5 The dataset contains 1843 genes, and … high rock lake campground lexington nc